The 24th International Conference on Knowledge and Systems Science (KSS2025) is the annual meeting of the International Society for Knowledge and Systems Science (http://www.iskss.org/). KSS2025 focuses on artificial intelligence and cross-disciplinary innovation, aiming to explore cutting-edge advancements and transformative paradigms in knowledge creation, systems thinking, and scientific discovery. Under the theme “AI-Driven Scientific Revolutions and Cross-Disciplinary Discovery”, KSS2025 will delve into the profound impact of artificial intelligence on accelerating scientific breakthroughs and fostering synergistic collaborations across disciplines. We invite researchers to submit original papers addressing challenges and opportunities at the intersection of AI-driven knowledge systems, interdisciplinary research frameworks, and governance of intelligent technologies. Join us in shaping the future of knowledge and systems science in Kitakyushu, Japan!